He isnt losing weight but really looks horrible. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications." Product Overview. It's not worth the risk of additional seizures or other neurological effects, and it seems that his stumbling and getting tired sooner on walks are likely related. She's wobbly on her feet and seems lopsided, although her eyes look ok; she is really lethargic and barely lifting her head. I took him to the emergency hosp. I'm so sorry. Head down, facing the wall, tremors, lethargic, and she can't seem to see well. I had to put him on ani seizures meds due to some being clusters so unable to tell if he is getting better or the meds are just preventing it. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. We are experiencing the same thing. The FDA considers products in the isoxazoline class to be safe and effective for dogs and cats but is providing this information so that pet owners and veterinarians can take it into consideration when choosing flea and tick products for their pets. I am so sorry to all of you and my heart goes out to you and your babies. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). Still waiting on the vet and waiting to talk to ASPCA poison control. Always confirm storage temperatures by reading the label. The vet has not been able to diagnose a cause. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death. Vet says Simparica is not the reason for his condition, but he was totally fine prior to taking Simparica!! The vet insisted it was not from the Simparica Trio. 1 dose of this Simperica Trio and he is completely different and cant hold his pee. (toy aussie & corgi). Drinking water and peeing excessively. Couple of days ago, I took my other doxie (Maddie) into my vet, for shots, he did the heart worm test and recommended Simparica. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. My little Billy Boy had his first visit to the vet and they gave him Simparica Trio. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. oh I should mention shadow is our 8 yr old dogue de Bordeaux - he has never had a reaction to anything ever before in his life and has never needed a vet so this was not usual at all for him .. My beautiful Golden was switched from her previous Medicine to this one. Her heartbeat was more of a vibration than a beat and the vet wanted her to see a cardiologist. Thank you for giving information on what happened to your dog. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. So far, the cost of diagnostic tests are about $700. How can they put something that can cause this level of damage on the market and how do vets not even tell us to monitor our pets or tell us what the risks are. My best friend's new puppy has had diarrhea for 14 days after taking one dose of Simparica. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. Im done with this drug! I am currently in the same situation and we are at day 16 after giving simparica. 10 days after taking Simparica, she started having muscle tremors. Today June 1,2022 she is still having neurological problems. She has good days and bad days but she is far from the dog she use to be. Side effects are uncommon, but may occur in some cases. Then suddenly dog has diarrhea and it lasted for several days. He has been on just Simparica with no problems. Neurologist doesnt seem to really know if the effects are long term or not. HELP!! He also got that odd cough here and there that I read someone else mention. Later in the fall I noticed some leg tremors when she squatted. How long did these symptoms last? Linda. and now i'm on an hour by hour let's see if she will perk up. Is Simparica only available with a prescription? Your veterinarian is the best source of information and will help you choose the right product for your dog and your budget. I am both incredibly sad and angry. However, doing nothing is better than giving her the Simparica. I cant believe how long this thread is. Like other oral treatments, Simparicaworks by entering a dogs bloodstream immediately after ingestion. Then we seen an ad on tv for Simparica and it mentioned seizures as a side effect. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. Please advise! Skin issues. The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. Simparico Trio, will not be given to my dog ever again. I am so sorry for your loss. Sometimes I think he is either blind or deaf. When fleas or ticks bite, they are exposed to its FDA-approved ingredient sarolaner, the insecticide, and acaricide that kills parasites fast. I will update once we have results from diagnostics. He had it once before with no issues. By June 7th, she had a rash over most of her body, itching and biting herself to bloody raw spots. Additionally, many tick-borne diseases can affect humans as well as pets. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. Decreased conscious proprioception. When did you stop giving the Simparico Trio? I can not find any information on a delayed reaction AND my Vet just discredits that its the Simparica because my dog goes to Daycare and could be exposed to other mystery things. I just hope and pray she gets better. He seems to be out of sorts, staring into space, getting freaked out when he can't see me (I thought he was losing his eyesight). Lost all appetite. Omg Im feeling sick seeing all these bad comments. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. He has no appetite and very little drinking either so hes not using the bathroom much. He has horrible water like stools. Has anyone experienced cardiac issues while under anesthesia on this medication? The simparica pushed his body into an Addison's Crisis - his body was literally shutting down. I'm so sorry. How is your puppy doing? I looked up side effects for this drug and was horrified to find that the flea med can cause tremors seizures and worse. MONEY!!. The Vet's are so busy that even if you can get in you don't get anywhere. This was the first time she was given this drug and will be the last. Contact your vet if your dog misses a month or more of heartworm preventionyour dog might have become infected with heartworm larvae. Especially, Camelia who lost her furbaby because of a seizure that was apparently brought on by this medication. Not to worry you, and I hope yours is different outcome! We tried stopping the simparica. Gave my dogs simparica and they both have lost their appetite! Youre an idiot then! How is your dog doing? 3 months ago he began having seizures, he had one every day for a week. 38 results for "simparica trio for dogs" RESULTS. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. So no Addisions. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. Two days later, she is doing better, but not 100% yet. Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. That is the only thing that has changed in her routine. The following list includes the known side effects of Simparica. Im convinced it was caused by this drug. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. He seems back to his normal self and playing with his toys, but we will not continue the following doses! She would constantly twirl in left circles. Some are also approved for treatment and control of ear mite infestations and some gastrointestinal parasite infections, and a few are also approved for prevention of heartworm disease. I will never give my dog this medication again. Then the following week 1 pill every other day . I would, still boil chicken, carrots, potatoes for his meals. He started having skin issues that the vet said were allergic reactions probably due to environmental things. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. This month 5/1 gave him another dose and here we are 12 days later with diarrhea and no appetite. Thank you. Went to a different vet, within minutes he found a large mass on my Poms abdomen. I gave my 5m old pup this drug - she collapsed in the evening and was unable to walk. I do believe it caused her blindness. Sunday, he was lethargic and refused to eat. Glad i held off on the free sample i was given! Our Vet suggested Simparica Trio! If she had just taken it they could give her Charcoal. Will not use this again and will warn others. The following day he would not even drink water. In such cases, please visit the veterinarian as soon as possible. We wont be using this medicine ever again! I gave my 10 year old Bull Terrier a dose of Simparico Trio Thursday December 3. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. He had a problem with severe biting a few months back and Vet said he most likely allergic to fleas (bites). I will NEVER give this drug to my dogs! He scratched at them which made it worse. I hope there will be a class action lawsuit but most importantly that the word get out to stop this medication from harming another life. She continued to have seizures even she was on phenobarbital. He seemed to get a little better over the next week until he woke at 5am vomiting and having diarrhea and very lethargic. We are already close to $2000 in Vet bills not counting the poison we bought her. Very common in: Dogs of any age, breed, or gender can experience vomiting. She uses drops 4 times a year on the top of the neck for fleas etc and told me to address the heart worm problem with the vet. Not even going to risk it . Side effects with Simparica are not common. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. You ask why they are giving this poison to our furbabies, it's easy. My Jack Russell Terrier has taken Simparica Trio for several months. In our case the damage was permanent. He is a 89 lbs 5 y/o pitbull who has never had any issues before. Just be aware that no oral tick medicine is safe, all are from the same class of drugs. My poor puppy has to go under anesthesia on top of. No way I will ever give it to her again. She has NEVER done that before. Omg my girl goes threw incredible itching this has lead to us takeing her to the vet because she gets infected from scratching herself to death. Generally, they may instruct you to administer it immediately when you remember and resume monthly dosing. When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal. After seeing his condition worsen, that night we took him to an after hours urgent care. He had to be put to sleep and Im devastated. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. I hope we get to the bottom of it as this is not fun. After reading all these reports I am convinced this is the reason our baby is so sick. 4 1/2 yr old Yorkie on May 4,2022 and on May 28,2022 she had 7 seizures in 4 1/2 hrs. Doing better now, 2 days later. Today she has fallen 2 or 3 times in the last 8 hours). Some years back my husband gave vet approved & sold oral flea/tic medication to each of our 2 Standard Poodles. She is lethargic and doesnt want to eat. They were good to deal with. Thank you for this information. This stuff should be banned. Then on day 5 my poor dog just couldnt move. In the meantime i keep trying to give him ice and i am very worried that i have permanently harmed him. I gave my black lab mix Simparica for the 1st time on 4/1. He wouldnt survive surgical attempt to go in and try to figure out what was going on. It is recommended to wash your hands after administering this medication. It is Easter Sunday and he still has diarrhea and drinking a crazy amount of water. I will not give it to my puppy again, but what is a safer med. We were so upset - I vowed to never use oral flea treatment again. Daily Paws is part of the Meredith National Digital Network. He is back to his old self now but we will never give him this medication again. The vet doesn't seem to really want to blame it on Simperica Trio and wants to treat these symptoms which he says are life threatening. Back to the vet and I hope they credit my money. But now I tell everyone just be aware that this product does have the potential to cause neurological harm. I hope and pray for no long term affects. My vet recommended the tablet to save on monthly costs for flea and tick treatment. On the first day he woke up and peed in my bedroom floor. This is terrible. I need to tell my vet to switch! I dont like that my dog looks at me like he doesnt know who I am. Hi, my dog is having these same issues right now and Im dying. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. Does any one think this could be a reaction to Simparico Trio? I'll be calling them tomorrow. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. Its crazy to think they dont recover and can die in a few months. They may not be ready to beat you in a game of chess, but these brainy dogs are easy to train and generally eager to please you. Some reports showed the dogs could have simparica seizures. The exact same thing is happening to my dog now. But few people read it or think it must be a million to one problem. And it looks like the liver and/or the kidney will not take it too. Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. In addition to the tremors, have you noticed any . Next day, he was suddenly 1000% worse, would not touch food, could not move. No more itching but covered in same scabs. Sound familiar? I fed him a diet of boiled chicken and rice for 3 days and began to introduce his food which is a limited ingredient type. They would clear up after a round of antibiotics but would return the next month. It is better but not gone. My 9 month old puppy started acting very lethargic after taking simparica trio. Keep the medication in the blister packs provided until ready to use in order to protect from moisture and light. have been seen after using medications in this class of drugs. I only researched it after he started not feeling well, just trusted my vet that this was safe. Never happened before. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. He is stumbling, not able to stand on tile or go in and out of house without tripping on steps. I must admit that I am pretty nervous about it, but we shall see. He had ONE dose that evening and completely lost his appetite within a couple days. Her last dose of Simparica Trio was given to her on October 1, 2021. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. How long do the side effects last? My personal dog has had no issues at all, and she's been on it for nearly two years. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. She has been the healthiest, happiest dog. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Puppy Simparico Trio for the first time 2 days ago. He is just laying in his crate . I will be discontinuing the medication. Our dog was killed by this poison within 15 hours after taking one dose. Then things got progressively worse. I will never give this again! My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Bravecto has six topical solutions for dogs by weight/size. Sarolaner, one of the ingredients, is a member of the isoxazoline class. Hi, how long it took for the diarrhea to go away. Im so terribly sorry about your puppy. Did you do this yourself or let the vet? We have been gradually increasing the dose but it hasnt helped. This is whats happening to our pup, can you please tell me how long it lasted? I just hope he has a turn around . I dont know what to do to get this out of their system?? Also - do NOT use Bravecto for females you intend to breed. Thankfully I have had experience with dealing with this with my kids and relatives so I dosed him with Benadryl. Simparica chewable is a preventative that is better suited to healthy adult dogs living in areas where ticks are prevalent. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. Im going to another vet and discontinuing simparica. I am trying to remain confident that my poor girl will recover. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. We will have blood work and results this evening. My dogs have been throwing up since then and I could not for the life of me figure out why. Any advice on the diarrhea? Do not give extra or double doses. Head bobbling and hind legs unable to support her - as if she were really drunk. just gave my one year old dauchund her first dose of simparica My vet didnt tell me, We gave our Yorkie this and she went into seizures later in the daywhat if any thing can be done. I am up writing this 4 a.m. since our Lambchop is too restless to sleep! I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). She has been diagnosed with thyroid problems and myocarditis. Im seeing an improvement in my dog, and am crossing fingers that this continues! I gave my dog his first dose April 8th. Don't risk the well-being of your beloved dog just because something is more convenient. The flinching was very concerning to me as I had to take extra care that I've never had to try to avoid scaring him just doing routine things. I am a physical therapist, and acquired Sadie to serve as a Therapy Dog in our clinic. Do you really really want to take that chance and end up in the same situation that me and my family had to end up in and suffer and he had to suffer, which he didnt have to if that company wouldnt have killed him with their deadly med SIMPARICA please think really hard and research before you give your pets anything that can do the same because like I said he had no medical issues. He was a normal dog before the medicine Simpatico Trio . My husband said that he felt like it would just make his coat shiny. After spending the day at the ER Vet where they did bloodwork and several x-rays all coming back normal, they sent her home with Keppra. Hopefully there are many other dogs that are unaffected, and just aren't written about here. If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. 12/18/21.. he did experience some diarrhea. Considerations Just like any other medication, Simparica has the potential to interact with other drugs your dog is taking. I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop. Has anyones dog stopped having seizures when the medication wore off or is this going to be a permanent issue possibly getting worse? By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. I also lost my dog due to simparia Trio. This is because it doesn't kill adult heartworms. She was ok for awhile, then she had a seizure and started throwing up all over the house. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. My 8 month old labradoodle has had 2 doses of Simparico Trio. How is ur puppy? Hoping you are the lucky ones!! Same thing has happened to my 5 month old puppy after taking simparica. before i even gave to my dog small doxie i asked the vet about it and they assured me it was safe since she was and i say was a healthy dog. She has been on it for 6 months. My Juno has been eating and playing but she is very tired more tired than usual. Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. Advised I could call Simparica for reimbursement or to report side effects. On 08/06 she threw up. Reading all of these comments I too think it is the drug that has caused his body to be toxic for him. I took him to the energy vet in the morning, he couldnt find any cause for pain, only he yelped a bit on his neck, they had trouble getting him in, he was yanking his neck around as he is afraid of the vet since getting fixed. Humans are another matter. After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. I called our Vet on the second day and they said they doubted very seriously that the Simparica would have give him diarrhea, and then told me that I should wait and see what happens with the next dose, because I had also told them that he had some drippings from some ground beef over his dog food the day before I gave him that first dose. They said , he has a Autoimmune Hemolytic anemia . It's 5:53pm and he's acting very lethargic. I got my dog Josey up to let him out to pee. She is scared of her own shadow, walks into things at times, trips and stumbles, has become very timid, stares at the wall and has to have either me or my husband in sight at all times. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. Things like: tremors decreased conscious proprioception ataxia reduced or absent menace, and or seizures Simparica is not recommended in lactating, pregnant females, or dogs used for breeding. Best of luck. Sadly and heartbroken I report a follow up that our healthy very active 7 yr old blue tick beagle did not make it - Frazier took his last breath on February 25 2021 - he only declined the seizures continued he was fatigued all the time started losing control of his bladder - and losing his balance and walking in circles we kept hoping that once the poison was out of him he would improve but sadly he only declined I spent many nites sitting with him because the seizures were getting so bad - we tried everything but our vet tried with us but on Feb 25th our vet said that Frazier had enough and he would not recover - I did contact the company as my vet recommended and the worst customer service reps especially in this situation all they wanted was his vet records in a very matter of fact tone as I kindly replied in southern style - kiss my biscuits!! The most common side effects of Simparica in dogs are vomiting and diarrhea. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." What Are Potential Simparica Trio Side Effects in Dogs? What do I do? around 12 years She grabs and won't let go. Side-Effects Of Simparica Trio Tablets There are some mild side effects like Vomiting Diarrhea Loss of appetite Dog owners should be aware that these tablets are not suitable for all dogs. I argued with the vet that this is poison and she said why would I give your dog poison? She's pacing and wants to eat grass. Many people have reported this as only temporary. It was the first time she had taken Simparica. Did anyone see any signs of improvement in their dogs? I PRAY that our baby is okay with this second dose. From classic to celeb-inspired and funny to food-based, this list of cute cat names is sure to inspire your naming adventures. Simparica, NexGard, Bravecto & Credelio may not increase the number of seizures, but the risk is real. We trusted our Vet when he recommended this over Revolution topical anti-tic/flea medication. He has never acted like he was in pain. We received the first dose of this medication from our Vet! Ticks are horrible here in Maine. Thank u Fox I have good news I did get 2 additional in house potassium test done and they both came back normal. Although vet wanted to treat him for Addison's I decided to wait it out and fortunately it worked out. He just isnt himself. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. Thanks all for sharing your experiences. From our vet giving my 70 lb golden doodle Trifexus, for Simparica they! 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Sorry to all of these comments i too think it is recommended to wash your hands administering... Dosed him with Benadryl bout of puppy strangles ( autoimmune disorder ) starting at 11 of! A permanent issue possibly getting worse having skin issues that the vet said he most likely allergic to (... Couch and was horrified to find that the vet has not been evaluated in breeding, pregnant, or can... Because it does not absorb well into the bloodstream 2 doses of Simparico Trio and.. Down, facing the wall, tremors, have you noticed any to having given Simparico. He seems back to his old self now but we will not continue the following he! What happened to your veterinarian have the potential to cause neurological harm his! And now i tell everyone just be aware that no oral tick medicine is safe, all are the... & amp ; Credelio may not increase the number of seizures, but may occur in cases. Product does have the potential to interact with other drugs your dog actually has meningitis then that would n't related. Diagnose a cause dog looks at me like he doesnt know who i am a physical therapist and!
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